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HOW RENIN CAN CONTRIBUTE
TO HIGH BLOOD PRESSURE

Renin is a chemical released by the kidneys. The body uses renin to regulate blood pressure. But sometimes the body's renin system doesn't work properly. When this happens, renin can contribute to high blood pressure. The tool below will help you learn about renin and high blood pressure, and how different high blood pressure treatments work to lower blood pressure.


The Renin System - Click “start” to see how renin can contribute to high blood pressure.
Start
Renin Is Released - When blood pressure goes down, the kidneys release a chemical into the bloodstream called RENIN.
Back Next
A Protein Is Split - RENIN splits a certain protein into pieces.
Back Next
The Reaction Continues - One of these pieces is split again by another chemical produced in your body called ACE.
Back Next
The Arteries Narrow - These new pieces constrict the walls of the small arteries, increasing blood pressure.
Back Next
Blood Pressure Increases - This protein also triggers the release of a hormone that causes the kidneys to retain salt. This can increase blood pressure.
Back Start Over
Click to view where treatments work in the renin system.
Blood Pressure Treatments
Renin Inhibitors - Renin Inhibitors work in step one to block the enzyme called RENIN.
ACE Inhibitors - ACE Inhibitors work in step two to block the chemical called ACE from splitting the protein.
ARBs - ARBs work in step three to block the protein pieces from narrowing the blood vessels.
Start Over Next: Blood Pressure Basics
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